Low-dose opioids should be considered for symptom relief also in advanced chronic obstructive pulmonary disease (COPD)
Open Access
- 6 January 2015
- journal article
- Published by BMJ in BMJ Evidence-Based Medicine
- Vol. 20 (1) , 39
Abstract
The main finding of the study should be emphasised: treatment with regular, low-dose opioids (≤30 mg oral morphine equivalents per day) was not associated with increased rates of hospitalisation or death in people with severe, oxygen-dependent COPD.Keywords
This publication has 5 references indexed in Scilit:
- Benzodiazepines and opioids need to be prescribed with caution in advanced COPDBMJ Evidence-Based Medicine, 2014
- Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective studyBMJ, 2014
- Once-Daily Opioids for Chronic Dyspnea: A Dose Increment and Pharmacovigilance StudyJournal of Pain and Symptom Management, 2011
- A most stubborn bias: no adjustment method fully resolves confounding by indication in observational studiesJournal of Clinical Epidemiology, 2010
- Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoeaBMJ, 2003