Fluorine-18-labeled PET radiotracers for imaging the macrophage colony-stimulating factor 1 receptor (CSF1R)
Open Access
- 11 January 2026
- journal article
- research article
- Published by Springer Nature in EJNMMI Radiopharmacy and Chemistry
- Vol. 11 (1)
Abstract
Positron emission tomography is a useful tool for quantitative imaging of neuroinflammation in human subjects; however, more suitable radiotracers are sougKeywords
Funding Information
- National Institute on Aging (AG066464)
This publication has 59 references indexed in Scilit:
- Inhibition of colony stimulating factor-1 receptor (CSF-1R) as a potential therapeutic strategy for neurodegenerative diseases: opportunities and challengesCellular and Molecular Life Sciences, 2022
- Recent developments on PET radiotracers for TSPO and their applications in neuroimagingActa Pharmaceutica Sinica B, 2021
- Critical evaluation of current Alzheimer’s drug discovery (2018–19) & futuristic Alzheimer drug model approachBioorganic Chemistry, 2019
- Imaging α4β2 Nicotinic Acetylcholine Receptors (nAChRs) in Baboons with [18F]XTRA, a Radioligand with Improved Specific Binding in Extra-Thalamic RegionsMolecular Imaging and Biology, 2016
- Direct comparison of radiation dosimetry of six PET tracers using human whole-body imaging and murine biodistribution studiesAnnals of Nuclear Medicine, 2013
- Systemic LPS causes chronic neuroinflammation and progressive neurodegenerationGlia, 2007
- Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitroGlia, 2001
- Regulation of MSCF receptors on microglia in the normal and injured mouse central nervous system: A quantitative immunofluorescence study using confocal laser microscopyJournal of Comparative Neurology, 1998
- Expression of the receptor for macrophage colony stimulating factor by brain microglia and its upregulation in brains of patients with Alzheimer's disease and amyotrophic lateral sclerosisBrain Research, 1994
- Colony stimulating factor-1 expression in human gliomaMolecular and Chemical Neuropathology, 1994