Improved Method for Collection of Nasal Mucus

Authors:
  • KPKeith R. Powell
    Keith R. Powell
  • RSRobert Shorr
    Robert Shorr
  • JCJames D. Cherry
    James D. Cherry
  • JHJ. Owen Hendley
    J. Owen Hendley
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Abstract
Specimens of nasal mucus obtained after stimulation of the mucosa with water and nasal washings from 20 volunteers were compared for content of IgA. The median concentration of IgA was 70 mg/dl in nasal mucus and 17 mg/dl in nasal washings concentrated 10-fold. The use of nasal mucus should allow for more accurate determination of nasal secretory antibody activity.