Computational Toxicology Experience and Applications for Risk Assessment in the Pharmaceutical Industry
Authors:
- Nigel GreeneNGNigel Greene
- Mark GosinkMGMark Gosink
- 1 January 2013
- book chapter
- Published by Elsevier
- p. 171-193
Abstract
No abstract availableKeywords
This publication has 104 references indexed in Scilit:
- Large-scale prediction and testing of drug activity on side-effect targetsNature, 2012
- Fast gapped-read alignment with Bowtie 2Nature Methods, 2012
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressureNature Genetics, 2011
- Analysis of Biological Processes and Diseases Using Text Mining Approaches2009
- Predicting new molecular targets for known drugsNature, 2009
- Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytesToxicology and Applied Pharmacology, 2009
- The liver pharmacological and xenobiotic gene response repertoireMolecular Systems Biology, 2008
- Quantifying the Relationships among Drug ClassesJournal of Chemical Information and Modeling, 2008
- Idiosyncratic drug hepatotoxicityNature Reviews Drug Discovery, 2005
- Key factors in the rising cost of new drug discovery and developmentNature Reviews Drug Discovery, 2004