Extranodal Rosai-Dorfman disease: an uncommon cause of persistent nodule in the ear

Authors:
  • JCJ. K. C. Chan
    J. K. C. Chan
  • WHW. K. Ho
    W. K. Ho
  • HYH. C. Yu
    H. C. Yu
  • LCL. T. C. Chow
    L. T. C. Chow
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Abstract
A 40-year-old woman presented with a nodule over the tragus of the right ear. A biopsy was initially reported as showing non-specific inflammation. In view of the persistence of the lesion, the histological material was reviewed, leading to revision of the diagnosis to Rosai-Dorfman disease, a diagnosis further confirmed by immunoreactivity of the histiocytes for s-100 protein. This case represented the extranodal form of Rosai-Dorfman disease in the absence of lymph node involvement.

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