Hsa_circ_0030042 regulates abnormal autophagy and protects atherosclerotic plaque stability by targeting eIF4A3
Authors:
Open Access
- 1 January 2021
- journal article
- research article
- Published by Ivyspring International Publisher in Theranostics
- Vol. 11 (11) , 5404-5417
Abstract
Rationale: Abnormal autophagic death of endothelial cells is detrimental to plaque structure as endothelial loss promotes lesional thrombosis. As emerging functional biomarkers, circular RNAs (circRNAs) are involved in various diseases, including cardiovascular. This study is aimed to determine the role of hsa_circ_0030042 in abnormal endothelial cell autophagy and plaque stability.Keywords
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