Recently, there has been an academic shift in which decolonial rhetoric has generated interesting discussions highlighting the need to protect and promote indigenous knowledge systems (IKS) towards a decolonial solution. In Botswana, an Indigenous knowledge book by Chilisa et al. advocates for decolonising research methods, suggesting it could lead to curriculum decolonisation. However, research methods that are aligned to Botswana IKS remain undeveloped and unapplied. The chapter is conceptualised on the Afrocentric methodological approach, which emphasises the importance of African people participating in the knowledge construction and the methodologies utilised. Simply put, Botswana communities should see themselves as active agents in knowledge generation. Afrocentricity operationalises decolonisation of research methods, placing the Botswana people at the centre of knowledge production concerning phenomena and broader global affairs. Botswana’s knowledge generation is guided by the philosophy of Botho, which enshrines several moral codes and developmental values, forming a basis for decolonial scholarship.