Induced Synthesis of Liver Microsomal Enzymes Which Metabolize Foreign Compounds
Authors:
- 27 November 1959
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 130 (3387) , 1478-1479
Abstract
The administration of 3,4-benzpyrene to rats markedly increases the activities of certain liver microsomal enzymes which metabolize foreign compounds. Evidence based on studies of enzyme induction is presented which suggests the presence in liver microsomes of several enzymes which can catalyze the same type of reaction.Keywords
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