A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish
Open Access
- 1 January 2008
- journal article
- Published by Springer Nature in BMC Ecology and Evolution
- Vol. 8 (1) , 42
Abstract
A large multigene family of NOD-like receptor (NLR) molecules have been described in mammals and implicated in immunity and apoptosis. Little information, however, exists concerning this gene family in non-mammalian taxa. This current study, therefore, provides an in-depth investigation of this gene family in lower vertebrates including extensive phylogenetic comparison of zebrafish NLRs with orthologs in tetrapods, and analysis of their tissue-specific expression.Keywords
This publication has 39 references indexed in Scilit:
- The immune gene repertoire encoded in the purple sea urchin genomeDevelopmental Biology, 2006
- Critical Role for Cryopyrin/Nalp3 in Activation of Caspase-1 in Response to Viral Infection and Double-stranded RNAJournal of Biological Chemistry, 2006
- Nod-like proteins in immunity, inflammation and diseaseNature Immunology, 2006
- Plant NBS-LRR proteins in pathogen sensing and host defenseNature Immunology, 2006
- Evolutionary relationships of vertebrate NACHT domain-containing proteinsImmunogenetics, 2006
- The Inflammasome: First Line of the Immune Response to Cell StressCell, 2006
- The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1β productionProceedings of the National Academy of Sciences, 2006
- Cryopyrin activates the inflammasome in response to toxins and ATPNature, 2006
- The CATERPILLER Protein Monarch-1 Is an Antagonist of Toll-like Receptor-, Tumor Necrosis Factor α-, and Mycobacterium tuberculosis-induced Pro-inflammatory SignalsJournal of Biological Chemistry, 2005
- Two Rounds of Whole Genome Duplication in the Ancestral VertebratePLOS Biology, 2005