Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats
Open Access
- 1 November 2014
- journal article
- research article
- Published by Elsevier in Neurobiology of Disease
- Vol. 71, 220-233
Abstract
No abstract availableKeywords
Funding Information
- Swedish Research Council (K2008-66X-20776-01-4, K2012-99X-20776-05-3)
- OH (2011-3457)
- GCB (K2011-80P-21816-01-4, K2011-80X-21817-01-4)
- Harald and Greta Jeanssons foundation
- Swedish Association for Persons with Neurological Disabilities
- Åke Wibergs Foundation
- Åke Löwnertz Foundation
- Swedish brain foundation
- David and Astrid Hagelén Foundation
- Swedish Society for Medical Research
- Swedish Society of Medicine
- Socialstyrelsen
- Karolinska Institutet
- Marie Curie Integration Grant, Seventh Framework Programme, European Union (PCIG12-GA-2012-333713)
- NeuroproMiSe (LSHM-CT-2005-018637)
- Theme Center for Regenerative Medicine at Karolinska Institutet
This publication has 59 references indexed in Scilit:
- Neural Stem Cell Differentiation Is Dictated by Distinct Actions of Nuclear Receptor Corepressors and Histone DeacetylasesStem Cell Reports, 2014
- Therapeutic Potential of Mood Stabilizers Lithium and Valproic Acid: Beyond Bipolar DisorderPharmacological Reviews, 2013
- Thyroid Hormones as Modulators of Immune Activities at the Cellular LevelThyroid®, 2011
- RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammationNature Immunology, 2011
- Inhibition of HDAC9 Increases T Regulatory Cell Function and Prevents Colitis in MiceGastroenterology, 2010
- Histone deacetylase inhibitor uses p21Cip1 to maintain anergy in CD4+ T cellsInternational Immunopharmacology, 2009
- Romidepsin for the treatment of cutaneous T-cell lymphomaDrugs of Today, 2009
- Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell functionBlood, 2006
- Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitisJournal of Neuroimmunology, 2005
- Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.Journal of Experimental Medicine, 1993