Novel diosgenin-1,4-quinone hybrids: Synthesis, antitumor evaluation, and mechanism studies
- 1 November 2021
- journal article
- research article
- Published by Elsevier in The Journal of Steroid Biochemistry and Molecular Biology
- Vol. 214, 105993
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (21672248, 21977115)
This publication has 41 references indexed in Scilit:
- Synthesis of diosgenin analogues as potential anti-inflammatory agentsThe Journal of Steroid Biochemistry and Molecular Biology, 2014
- Synthesis of New Quinolinequinone Derivatives and Preliminary Exploration of their Cytotoxic PropertiesJournal of Medicinal Chemistry, 2013
- NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinonesBiochemical Pharmacology, 2012
- Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cellsCancer Letters, 2010
- The anti-cancer, anti-inflammatory and tuberculostatic activities of a series of 6,7-substituted-5,8-quinolinequinonesBioorganic & Medicinal Chemistry, 2010
- Hybrid Molecules with a Dual Mode of Action: Dream or Reality?Accounts of Chemical Research, 2007
- An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachoneProceedings of the National Academy of Sciences, 2007
- Arsenite pretreatment enhances the cytotoxicity of mitomycin C in human cancer cell lines via increased NAD(P)H quinone oxidoreductase 1 expressionToxicology and Applied Pharmacology, 2006
- Natural Product Hybrids as New Leads for Drug DiscoveryAngewandte Chemie International Edition, 2003
- β-Lapachone-Induced Apoptosis in Human Prostate Cancer Cells: Involvement of NQO1/xip3Experimental Cell Research, 2001