Phase II study of ASA404 (vadimezan, 5,6-dimethylxanthenone-4-acetic acid/DMXAA) 1800mg/m2 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer
Authors:
- Mark J. McKeageMMMark J. McKeage
- Martin ReckMRMartin Reck
- Michael B. JamesonMJMichael B. Jameson
- David GibbsDGDavid Gibbs
- Paul N. MainwaringPMPaul N. Mainwaring
- Lutz FreitagLFLutz Freitag
- Richard SullivanRSRichard Sullivan
- Joachim Von PawelJPJoachim Von Pawel
- 1 August 2009
- journal article
- research article
- Published by Elsevier in Lung Cancer
- Vol. 65 (2) , 192-197
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung CancerNew England Journal of Medicine, 2006
- Disrupting tumour blood vesselsNature Reviews Cancer, 2005
- Randomized Phase II Trial Comparing Bevacizumab Plus Carboplatin and Paclitaxel With Carboplatin and Paclitaxel Alone in Previously Untreated Locally Advanced or Metastatic Non-Small-Cell Lung CancerJournal of Clinical Oncology, 2004
- Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in miceBritish Journal of Cancer, 2004
- Phase I Trial of the Antivascular Agent Combretastatin A4 Phosphate on a 5-Day Schedule to Patients With Cancer: Magnetic Resonance Imaging Evidence for Altered Tumor Blood FlowJournal of Clinical Oncology, 2003
- Phase I Clinical Trial of Weekly Combretastatin A4 Phosphate: Clinical and Pharmacokinetic ResultsJournal of Clinical Oncology, 2003
- Antivascular therapy of cancer: DMXAAThe Lancet Oncology, 2003
- Phase III Randomized Trial Comparing Three Platinum-Based Doublets in Advanced Non–Small-Cell Lung CancerJournal of Clinical Oncology, 2002
- Induction of endothelial cell apoptosis by the antivascular agent 5,6-dimethylxanthenone-4-acetic acidBritish Journal of Cancer, 2002
- Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acidBritish Journal of Cancer, 1995