Electrophorus Adenosine Triphosphatase: Sodium-Activated Exchange after N -Ethyl Maleimide Treatment
Authors:
- 17 July 1964
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 145 (3629) , 283-284
Abstract
The microsomal fraction from the electric organ of the eel Electrophorus electricus catalyzes the hydrolysis of adenosine triphosphate in the presence of Mg ++ , Na + , and K + . The same preparation catalyzes a Mg ++ -dependent transphosphorylation between adenosine triphosphate and adenosine diphosphate. Both of these reactions are inhibited after treatment of the microsomes with N -ethyl maleimide. However, the addition of Na + reactivates the transphosphorylation, and the rate becomes more rapid than that of the original. This new Na + -sensitive exchange reaction is believed to be a component of the hydrolytic reaction.Keywords
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