The bone morphogenetic protein–hepcidin axis as a therapeutic target in inflammatory bowel disease
Open Access
- 1 January 2012
- journal article
- research article
- Published by Oxford University Press (OUP) in Inflammatory Bowel Diseases
- Vol. 18 (1) , 112-119
Abstract
Background. A debilitating anemia associated with low serum iron often accompanies inflammatory bowel disease (IBD). Increased production of the iron rKeywords
This publication has 42 references indexed in Scilit:
- BMP6 Treatment Compensates for the Molecular Defect and Ameliorates Hemochromatosis in Hfe Knockout MiceGastroenterology, 2010
- Iron Sequestration and Anemia of InflammationSeminars in Hematology, 2009
- Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of HemochromatosisGastroenterology, 2009
- Bone morphogenetic protein receptors and signal transductionThe Journal of Biochemistry, 2009
- BMP6 is a key endogenous regulator of hepcidin expression and iron metabolismNature Genetics, 2009
- Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin ExpressionCell Metabolism, 2009
- T cell transfer model of chronic colitis: concepts, considerations, and tricks of the tradeAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2009
- The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin ExpressionCell Metabolism, 2008
- Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolismNature Chemical Biology, 2007
- Impaired intestinal iron absorption in Crohnʼs disease correlates with disease activity and markers of inflammationInflammatory Bowel Diseases, 2006