Design of novel focal adhesion kinase inhibitors using 3D-QSAR and molecular docking
Authors:
- 28 September 2013
- journal article
- Published by Springer Nature in Medicinal Chemistry Research
- Vol. 23 (4) , 1976-1997
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastomaCell Cycle, 2010
- Sunitinib and PF-562,271 (FAK/Pyk2 inhibitor) effectively block growth and recovery of human hepatocellular carcinoma in a rat xenograft modelCancer Biology & Therapy, 2009
- FXR Promotes Endothelial Cell Motility Through Coordinated Regulation of FAK and MMP-9Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
- Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumorsCancer, 2008
- TAE226 Inhibits Human Neuroblastoma Cell SurvivalCancer Investigation, 2008
- Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2Bioorganic & Medicinal Chemistry Letters, 2006
- Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 1Bioorganic & Medicinal Chemistry Letters, 2006
- Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.Molecular and Cellular Biology, 1994
- Sample-distance partial least squares: PLS optimized for many variables, with application to CoMFAJournal of Computer-Aided Molecular Design, 1993
- Validation of the general purpose tripos 5.2 force fieldJournal of Computational Chemistry, 1989