Parotid Gland Tumors: Can Addition of Diffusion-weighted MR Imaging to Dynamic Contrast-enhanced MR Imaging Improve Diagnostic Accuracy in Characterization?

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Abstract
Purpose: To determine the value of adding diffusion-weighted (DW) magnetic resonance (MR) imaging to dynamic contrast material–enhanced MR imaging when distinguishing between benign and malignant parotid tumors. Materials and Methods: This retrospective study was approved by the institutional review board, and the informed consent requirement was waived. The authors analyzed MR images of 50 lesions (36 benign, 14 malignant) in 47 patients. DW MR imaging and dynamic contrast-enhanced MR imaging were performed in all patients. Time-intensity curve (TIC) patterns were categorized as follows: type A, time to peak was more than 120 seconds; type B, time to peak was 120 seconds or less with high washout ratio (≥30%); type C, time to peak was 120 seconds or less with low washout ratio (<30%); and type D, flat. The apparent diffusion coefficient (ADC) values were measured on DW MR images. Sensitivity, specificity, accuracy, and positive and negative predictive values were calculated for type A, B, and D tumors re...

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