Comparative Genomics of Herpes Simplex Virus 2 Isolated from a Maternal-Neonatal Dyad Reveals High Consensus Sequence Homology as Well as Minor Variant Diversity
- 24 July 2026
- journal article
- Published by Oxford University Press (OUP) in Journal of the Pediatric Infectious Diseases Society
- Vol. 15 (8)
Abstract
Neonatal herpes simplex virus disease most often occurs following mother-to-neonate transmission during childbirth. However, genomic differences between the maternal and neonatal viral populations are poorly understood. Here, we performed deep whole-genome sequencing of clinical HSV-2 samples obtained from a maternal-neonatal dyad to investigate viral population dynamics during transmission.Keywords
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