Reducing Hospitalizations and Multidrug-Resistant Organisms via Regional Decolonization in Hospitals and Nursing Homes

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Abstract
Antimicrobial resistance threatens global health.1,2 Compared with antimicrobial-susceptible organisms, infections due to multidrug-resistant organisms (MDROs) are more difficult to treat with increased morbidity, mortality, length of hospitalization, and health care costs.3 Moreover, the emergence of MDROs continues to outpace the development of new antimicrobials, contributing to increasing infections without effective treatments.1 With limited therapeutic options, action is warranted to mitigate MDRO burden and spread, especially in health care settings.

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