Neuro-Behçet Syndrome Triggered by Illicit Drug Use: Case Presentation and Literature Review
Authors:
- Maltepe University Hospital-Department of Internal MedicineMMMaltepe University Hospital-Department of Internal Medicine
- Pinar MertPMPinar Mert
- Fatih Öner KayaFKFatih Öner Kaya
- Atakan YükselAYAtakan Yüksel
- Selim NalbantSNSelim Nalbant
- Miruna Florentina AteşMAMiruna Florentina Ateş
- Maltepe University Hospital-Department of NeurologyMNMaltepe University Hospital-Department of Neurology
Open Access
- 3 February 2025
- journal article
- Published by Opast Group LLC in Advances in Neurology and Neuroscience
- Vol. 8 (1) , 01-06
Abstract
Behcet's disease is a chronic systemic inflammatory disorder that is characterized by recurrent oral and genital aphthous ulcers, skin lesions, uveitis, as well as the involvement of different organs, including the central nervous system (CNS) [1]. Neurological manifestations, better known as neuro-Behcet's (NB), occur in about 5-10% of cases, ranging from headaches and impaired cognition to severe neurological deficits [2,3]. This case report describes a unique case of neuro-Behcet's disease in a patient with substance use in the background, and it adds to knowledge while enhancing further understanding of this complex interplay and its implications regarding managementKeywords
This publication has 35 references indexed in Scilit:
- Myelin basic protein and index for neuro-Behçet's diseaseClinical Immunology, 2023
- Immunology of Neuro-Behcet’s Disease (NBD)2021
- The blood-brain barrier in neuroimmunology: Tales of separation and assimilationBrain, Behavior, and Immunity, 2015
- Immune system inflammation in cocaine dependent individuals: implications for medications developmentHuman Psychopharmacology: Clinical and Experimental, 2012
- Interleukin-6 in neuro-Behçet’s disease: Association with disease subsets and long-term outcomeCytokine, 2008
- Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-elementExperimental Eye Research, 2008
- Effects of Cocaine and Morphine Withdrawal on the Immune Response2006
- Cerebrospinal fluid β2-microglobulin in neuro-Behçet’s syndromeJournal of the Neurological Sciences, 2000
- Brain capillary lesions produced by cocaine in ratsToxicology Letters, 1997
- Humoral and Cellular Immunologic Study of Cerebrospinal Fluid in a Patient With Behcet EncephalitisArchives of Neurology, 1992