Species-specific cleavage of the autophagy adaptor p62 dictates responses to TNF
Authors:
- Christoph NössingCNChristoph Nössing
- Olga TroitskayaOTOlga Troitskaya
- Jaclyn S. LongJLJaclyn S. Long
- Andrew CraxtonACAndrew Craxton
- Martina BrucoliMBMartina Brucoli
- Eve AndersonEAEve Anderson
- Sergio LillaSLSergio Lilla
- David G. McEwanDMDavid G. McEwan
- Annabel R. MintonAMAnnabel R. Minton
- Valentin J.A. BarthetVBValentin J.A. Barthet
- Gemma ThomsonGTGemma Thomson
Open Access
- 7 April 2026
- journal article
- Published by Elsevier in Molecular Cell
- Vol. 86 (8) , 1574-1586.e11
Abstract
No abstract availableKeywords
Funding Information
- Medical Research Council
- Beatson Institute for Cancer Research
This publication has 71 references indexed in Scilit:
- Caspase-8: The double-edged swordBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2020
- The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomicsMass Spectrometry Reviews, 2017
- Application of CRISPR/Cas9 to Autophagy Research2017
- RIPK3 regulates p62–LC3 complex formation via the caspase-8-dependent cleavage of p62Biochemical and Biophysical Research Communications, 2015
- Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degenerationActa Neuropathologica, 2014
- RIP Kinases at the Crossroads of Cell Death and SurvivalCell, 2009
- Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis SignalingCell, 2009
- Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB ActivationCell, 2009
- TNF-α Induces Two Distinct Caspase-8 Activation PathwaysCell, 2008
- LC3 conjugation system in mammalian autophagyThe International Journal of Biochemistry & Cell Biology, 2004