Myocardial Tc-99m MDP Uptake on a Bone Scan in Senile Systemic Amyloidosis with Cardiac Involvement

Authors:
  • EVErkan Vardareli̇
    Erkan Vardareli̇
  • OEOğuz Erdi̇nĉ
    Oğuz Erdi̇nĉ
  • EKEmi̇ne Kasapoğlu
    Emi̇ne Kasapoğlu
  • NANecmi̇ Ata
    Necmi̇ Ata

Abstract
A Tc-99m MDP bone scan showed diffuse myocardial uptake in a 61-year-old man who reported progressive glove- and stocking-like parasthesias. Results of complete blood counts, thyroid and liver function tests, tumor markers, electrolytes, and electrocardiography were normal. Electromyelographic findings revealed bilateral sensorimotor peripheral polyneuropathy in both upper and lower extremities. Monoclonal immunoglobulin light chains were not detected in serum or urine by immunoelectrophoresis. Amyloid deposition was noted on the histologic analyses of rectal biopsy samples. Results of immunohistochemical staining were positive. There were no clinical signs of cardiac functional impairment. Follow-up investigations did not reveal any other site of amyloid deposition, and the only symptoms were peripheral neuropathy.

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