The Two Period Binary Response Cross‐Over Trial
Authors:
- 1 January 1986
- journal article
- research article
- Published by Wiley in Biometrical Journal
- Vol. 28 (7) , 863-869
Abstract
The cross‐over design for clinical trials when responses are binary is discussed. Three tests which have been proposed for the analysis of this problem are compared by an assessment of their assumptions. A simple test to establish whether it is appropriate to include observations from the second period is presented.Keywords
This publication has 8 references indexed in Scilit:
- Change-Over Clinical Trial with Binary Data: Mixed-Model-Based Comparison of TestsBiometrics, 1984
- The Two-Period Crossover TrialJournal of the Royal Statistical Society: Series D (The Statistician), 1982
- The Comparison of Success Rates in Cross-Over Trials in the Presence of an Order EffectJournal of the Royal Statistical Society Series C: Applied Statistics, 1981
- The Crossover Experiment for Clinical Trials1980
- Model building and testing for the change‐over designBiometrical Journal, 1980
- Testing Hypotheses in the Two‐period Change‐over with Binary DataBiometrical Journal, 1978
- An exact test for comparing matched proportions in crossover designsBiometrika, 1969
- The Two-Period Change-Over Design and Its Use in Clinical TrialsBiometrics, 1965