Facile route for the synthesis of benzothiazoles and benzimidazoles in the presence of tungstophosphoric acid impregnated zirconium phosphate under solvent‐free conditions
- 1 January 2009
- journal article
- research article
- Published by Wiley in Heteroatom Chemistry
- Vol. 20 (4) , 202-207
Abstract
Rapid and efficient condensation reactions of o‐phenylenediamine and o‐aminothiophenol with various aldehydes were carried out using tungstophosphoric acid impregnated zirconium phosphate in solvent‐free conditions to afford the corresponding 2‐substituted arylbenzimidazole and arylbenzothiazole derivatives in good to excellent yields. This procedure constitutes a simple and practical green synthetic method for 2‐arylbenzimidazoles and 2‐arylbenzothiazoles and their structural analogs. Furthermore, the catalyst can be reused for several times but it will be less active. © 2009 Wiley Periodicals, Inc. Heteroatom Chem 20:202–207, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20534Keywords
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