Copper Metal Organic Polyhedron (Cu-MOP) Hydrogel as Responsive Cytoprotective Shell for Living Cell Encapsulation

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Abstract
Single-cells coated with functional shells to protect them from external harsh condition have great potential applications in many fields, such as tissue engineering, cell-based devices, cell biology and so on. Herein, copper metal organic polyhedron (Cu-MOP) hydrogel has been applied as a soft shell for cell protection under both physical and chemical stimulations. Comparing with previous strategy, this MOP-Gel shell not only possesses more satisfied protection effect, but also can be prepared and removed facilely without any damages to the encapsulated cells.
Funding Information
  • National Natural Science Foundation of China (21765024, 21964020)
  • Science and Technology Program of Quanzhou (2018N118S)

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