Supplemental Breast Cancer Screening with Contrast-enhanced Mammography or Abbreviated MRI for Extremely Dense Breasts: The DENSE-2 Trial
Authors:
- Sophie E. L. van GrinsvenSGSophie E. L. van Grinsven
- Evelyn M. MonninkhofEMEvelyn M. Monninkhof
- Ritse M. MannRMRitse M. Mann
- Mireille J. M. BroedersMBMireille J. M. Broeders
- Nicolien T. van RavesteynNRNicolien T. van Ravesteyn
- Monique D. DorriusMDMonique D. Dorrius
- Katya M. DuvivierKDKatya M. Duvivier
- Mathijn D. F. de JongMJMathijn D. F. de Jong
- 1 October 2026
- journal article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 321 (1)
Abstract
The Dense Tissue and Early Breast Neoplasm Screening-2 (DENSE-2) trial addresses whether supplemental contrast-enhanced mammography and abbreviated MRI can lead to fewer interval cancers in women with extremely dense breasts compared with mammography.Keywords
Funding Information
- ZonMw (05550412310002)
This publication has 29 references indexed in Scilit:
- The association between intrinsic breast cancer subtypes, mammography screening and prognosis: a large population-based real world cohort studyThe Breast, 2025
- Comparison of supplemental breast cancer imaging techniques—interim results from the BRAID randomised controlled trialThe Lancet, 2025
- Clinical outcomes by breast cancers diagnostic modes: A comprehensive evaluation of a national breast cancer screening programmeCancer Epidemiology, 2025
- Evaluating ten years of breast cancer screening with contrast enhanced mammography in women with Intermediate-high riskEuropean Journal of Radiology, 2024
- Breast Cancer Screening for Women at Higher-Than-Average Risk: Updated Recommendations From the ACRJournal of the American College of Radiology, 2023
- Interval Breast Cancers Versus Screen Detected Breast Cancers: A Retrospective Cohort StudyAcademic Radiology, 2023
- Tumour characteristics of screen-detected and interval cancers in the Flemish Breast Cancer Screening Programme: A mammographic breast density studyMaturitas, 2022
- Breast cancer screening in women with extremely dense breasts recommendations of the European Society of Breast Imaging (EUSOBI)European Radiology, 2022
- Volumetric breast density affects performance of digital screening mammographyBreast Cancer Research and Treatment, 2016
- Breast cancer screening halves the risk of breast cancer death: A case-referent studyThe Breast, 2014