Chronic myeloid leukemia from basics to bedside
Authors:
Open Access
- 1 November 1999
- journal article
- review article
- Published by Springer Nature in Leukemia
- Vol. 13 (11) , 1646-1674
Abstract
The discovery of the Philadelphia chromosome and its consistent involvement in chronic myeloid leukemia (CML) was the first time that a relationship between a cytogenetic abnormality and malignancy was demonstrated. This review will try to provide an insight into the molecular mechanisms underlying this disease and outline the therapeutical options for patients with CML.Keywords
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