Genomic medicine on the frontier of precision medicine
- 24 August 2021
- journal article
- review article
- Published by Springer Nature in Journal of Diabetes & Metabolic Disorders
- Vol. 21 (1) , 853-861
Abstract
Genomic medicine has created a great deal of hope since the completion of the Human Genome Project (HGP). Genomic medicine promises disease prevention and early diagnosis in the context of precision medicine. Precision medicine as a scientific discipline has introduced as an evolution in medicine. The rapid growth of high-development technologies permits the assessment of biological systems. Study of the integrated profiles of omics, such as genome, transcriptome, proteome and other omics information lead to significant advances in personalized and precision medicine. In the context of precision medicine, pharmacogenomics can play an important role in order to discriminate responders and non-responders to medications and avoiding toxicity and achieving the optimum dose. So precision medicine in accordance with genomic medicine will transform medicine from conventional evidence-based medicine in the diagnosis and treatment towards precision based-medicine. In this review, we have summarized the related issues for genomic medicine and precision medicine.Keywords
This publication has 40 references indexed in Scilit:
- Pharmacogenetics and personalized treatment of type 2 diabetesBiochemia Medica, 2013
- The discovery of human genetic variations and their use as disease markers: past, present and futureJournal of Human Genetics, 2010
- A haplotype map of the human genomeNature, 2005
- Finishing the euchromatic sequence of the human genomeNature, 2004
- The International HapMap ProjectNature, 2003
- Large-scale genotyping of complex DNANature Biotechnology, 2003
- Efficient selective screening of haplotype tag SNPsBioinformatics, 2003
- A Bacterial Artificial Chromosome Library for Sequencing the Complete Human GenomeGenome Research, 2001
- Initial sequencing and analysis of the human genomeNature, 2001
- A New Five-Year Plan for the U.S. Human Genome ProjectScience, 1993