Association of High-Volume Centers With Survival Outcomes Among Patients With Nontraumatic Out-of-Hospital Cardiac Arrest
Authors:
Open Access
- 31 May 2022
- journal article
- review article
- Published by American Medical Association (AMA) in JAMA Network Open
- Vol. 5 (5) , e2214639
Abstract
Out-of-hospital cardiac arrest (OHCA) is a time-critical medical emergency that results in substantial disease burden.1,2 Outcomes in OHCA can be poor despite the return of spontaneous circulation3 because post–cardiac arrest syndrome, a systemic ischemia-reperfusion injury, is a major contributor to mortality and morbidity in patients with OHCA.4 Consequently, post–cardiac arrest care has been advocated as the fifth link in the chain of survival.5 Considering the advanced treatment required, such as targeted temperature management (TTM) and percutaneous coronary intervention (PCI), specialized tertiary centers with access to such facilities are recommended to manage cases of OHCA.6-8Keywords
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