Protein Kinase C-mediated Down-regulation of Cyclin D1 Involves Activation of the Translational Repressor 4E-BP1 via a Phosphoinositide 3-Kinase/Akt-independent, Protein Phosphatase 2A-dependent Mechanism in Intestinal Epithelial Cells
Authors:
- Kyung SongKSKyung Song
- Marybeth A. PyszMPMarybeth A. Pysz
- Kathryn J. CurryKCKathryn J. Curry
- A. Asli HizliAHA. Asli Hizli
- David DanielpourDDDavid Danielpour
- Adrian R. BlackABAdrian R. Black
- Jennifer D. BlackJBJennifer D. Black
Open Access
- 1 May 2007
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 282 (19) , 14213-14225
Abstract
No abstract availableKeywords
This publication has 108 references indexed in Scilit:
- Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1α binding to PIAS1Molecular and Cellular Endocrinology, 2007
- Protein Kinase C α but not PKCζ Suppresses Intestinal Tumor Formation in ApcMin/+ MiceCancer Research, 2006
- Protein Kinase C α Signaling Inhibits Cyclin D1 Translation in Intestinal Epithelial CellsJournal of Biological Chemistry, 2006
- Integrin–protein kinase C relationshipsBiochemical Society Transactions, 2003
- dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1Nature Cell Biology, 2002
- Lysophosphatidylcholine Inhibits Insulin-Induced Akt Activation Through Protein Kinase C-α in Vascular Smooth Muscle CellsHypertension, 2002
- A Quantitative Molecular Model for Modulation of Mammalian Translation by the eIF4E-binding Protein 1Journal of Biological Chemistry, 2001
- Multiple Mechanisms Control Phosphorylation of PHAS-I in Five (S/T)P Sites That Govern Translational RepressionMolecular and Cellular Biology, 2000
- Protein Kinase C Modulates the Insulin-Stimulated Increase in Akt1 and Akt3 Activity in 3T3-L1 AdipocytesBiochemical and Biophysical Research Communications, 1998
- Five of six protein kinase C isoenzymes present in normal mucosa show reduced protein levels during tumor development in the human colonCarcinogenesis, 1994