Electrochemical Oxidation Mechanisms of the Antioxidants Daidzein and 7‐Hydroxy‐4‐chromone
- 16 February 2012
- journal article
- conference paper
- Published by Wiley in Electroanalysis
- Vol. 24 (3) , 618-626
Abstract
The electrochemical behavior of antioxidants daidzein (DZ) and 7‐hydroxy‐4‐chromone (7‐OH‐4‐CHM) was investigated. The oxidation of DZ is irreversible, pH‐dependent, and occurs in two steps, the first of 4′‐OH on the B‐ring and the second on the 7‐OH on the A‐ring. The oxidation of 7‐OH‐4‐CHM occurs on the 7‐OH on the A‐ring, is irreversible, pH‐dependent and proceeds in a single step. The DZ diffusion coefficient was calculated in pH 7.0 phosphate buffer to beDDZ=8.1×10−5 cm2 s−1. The detection limits of DZ and 7‐OH‐4‐CHM was calculated asLODDZ=0.08 µM andLOD7‐OH‐4‐CHM=0.13 µM.Keywords
This publication has 29 references indexed in Scilit:
- Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophagesBioorganic & Medicinal Chemistry, 2010
- Electrochemical Characterization and Quantification of the Strong Antioxidant and Antitumor Agent PomiferinElectroanalysis, 2009
- Comparison of Flavonoids and Isoflavonoids as AntioxidantsJournal of Agricultural and Food Chemistry, 2009
- Daidzein as an Antioxidant of Lipid: Effects of the Microenvironment in Relation to Chemical StructureJournal of Agricultural and Food Chemistry, 2008
- Simultaneous determination of daidzein, equol, genistein and bisphenol A in human urine by a fast and simple method using SPE and GC‐MSMolecular Nutrition & Food Research, 2007
- Dietary effects of soy isoflavones daidzein and genistein on 7,12-dimethylbenz[a]anthracene-induced mammary mutagenesis and carcinogenesis in ovariectomized Big Blue transgenic ratsCarcinogenesis, 2006
- Electrochemical Oxidation of QuercetinElectroanalysis, 2003
- Improved Method for Gas Chromatographic Analysis of Genistein and Daidzein from Soybean (Glycine max) SeedsJournal of Agricultural and Food Chemistry, 1999
- Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancerJournal of Cellular Biochemistry, 1995
- Soy intake and cancer risk: A review of thein vitroandin vivodataNutrition and Cancer, 1994