Special Feature: Heuristic Models of Comorbidity of Axis I and Axis II Disorders

Authors:
  • PTPeter Tyrer
    Peter Tyrer
  • JGJohn Gunderson
    John Gunderson
  • MTMauricio Tohen
    Mauricio Tohen

Abstract
The mechanisms responsible for the co-occurrence of personality disorders with Axis I disorders are not well understood. We propose a number of models that include various relationships at the etiological, pathophysiological, and observable clinical levels between personality disorders and Axis I disorders. It is recommended that such models be subjected to empirical tests to assess their validity.