Long-term Efficacy of Platelet Glycoprotein IIb/IIIa Integrin Blockade With Eptifibatide in Coronary Stent Intervention

Authors:
  • CBChristopher E. Buller
    Christopher E. Buller
  • WCWarren J. Cantor
    Warren J. Cantor
  • ACA. Bleakley Chandler
    A. Bleakley Chandler
  • ECEric A. Cohen
    Eric A. Cohen
  • DCDavid J. Cohen
    David J. Cohen
  • NKNeal S. Kleiman
    Neal S. Kleiman
  • MLMarino Labinaz
    Marino Labinaz
  • MMMina Madan
    Mina Madan
  • GHGail E. Hafley
    Gail E. Hafley
  • RCRobert M. Califf
    Robert M. Califf

Abstract
Over the past decade, evidence has documented the efficacy of intravenous platelet glycoprotein (Gp) IIb/IIIa integrin blockade as an adjunct to percutaneous coronary intervention (PCI).1,2 Blockade of the Gp IIb/IIIa receptor reduces ischemic complications of PCI across all indications for PCI, among the various devices used for PCI, throughout a broad range of heparin anticoagulation strategies, and across several different agents.3-8