Making sense of human colorectal cancer molecular subtypes: mice are stepping in

This publication has 11 references indexed in Scilit:

• Dipeptidase-1–knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer
  JCI Insight, 2025
• Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability
  Nature Communications, 2025
• Signaling pathways involved in colorectal cancer: pathogenesis and targeted therapy
  Signal Transduction and Targeted Therapy, 2024
• Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis
  Nature Communications, 2023
• BRAFV600E-mutated serrated colorectal neoplasia drives transcriptional activation of cholesterol metabolism
  Communications Biology, 2023
• Increased mitochondrial proline metabolism sustains proliferation and survival of colorectal cancer cells
  PLOS ONE, 2022
• A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis
  Cancers, 2021
• Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
  Cancer Cell, 2019
• Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes
  Scientific Reports, 2018
• KRAS and BRAF Mutations in Advanced Colorectal Cancer Are Associated With Poor Prognosis but Do Not Preclude Benefit From Oxaliplatin or Irinotecan: Results From the MRC FOCUS Trial
  Journal of Clinical Oncology, 2009