Inverted terminal repetition in vaccinia virus DNA encodes early mRNAs
Authors:
- Riccardo WittekRWRiccardo Wittek
- Ernest BarbosaEBErnest Barbosa
- Jonathan A. CooperJCJonathan A. Cooper
- Claude F. GaronCGClaude F. Garon
- Hardy ChanHCHardy Chan
- Bernard MossBMBernard Moss
- 1 May 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 285 (5759) , 21-25
Abstract
Vaccinia virus DNA contains a long inverted terminal repetition of MW approximately 6.8 x 10(6). A fragment of MW 6.3 X 10(6) from this repetition has been cloned in coliphage lambda and used to isolate RNA from virus-infected cells. Electron microscopy indicates that early RNAs are transcribed from the repeated sequence and cell-free translation shows that the RNAs code for polypeptides.Keywords
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