Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and α-adrenolytic activity
- 1 October 2005
- journal article
- Published by Elsevier in Il Farmaco
- Vol. 60 (10) , 793-803
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activityEuropean Journal of Medicinal Chemistry, 2002
- Different Subtypes of α1-Adrenoceptor Modulate Different K+ Currents via Different Signaling Pathways in Canine Ventricular MyocytesJournal of Biological Chemistry, 2001
- Structure−Activity Studies for a Novel Series of Bicyclic Substituted Hexahydrobenz[e]isoindole α1A Adrenoceptor Antagonists as Potential Agents for the Symptomatic Treatment of Benign Prostatic HyperplasiaJournal of Medicinal Chemistry, 2001
- Chapter 20. Toward the development of α1a adrenergic receptor antagonists2000
- Synthesis, antiarrhythmic and hypotensive activity of some novel 1,3-disubstituted ureas and phenyl N-substituted carbamatesEuropean Journal of Medicinal Chemistry, 1998
- Pharmacological Options in the Treatment of Benign Prostatic HyperplasiaJournal of Medicinal Chemistry, 1997
- Search for New Antiarrhythmic and Hypotensive Compounds. Synthesis, Antiarrhythmic, Antihypertensive, and α‐Adrenoceptor Blocking Activity of Novel 1‐[(2‐Hydroxy‐3‐amino)]‐propylpyrrolidin‐2‐one DerivativesArchiv der Pharmazie, 1997
- THE USE OFα-ADRENOCEPTOR ANTAGONISTS IN THE PHARMACOLOGICAL MANAGEMENT OF BENIGN PROSTATIC HYPERTROPHY: AN OVERVIEWPharmacological Research, 1996
- Increased alpha-adrenergic receptors in ischemic cat myocardium. A potential mediator of electrophysiological derangements.Journal of Clinical Investigation, 1981
- Alpha adrenergic contributions to dysrhythmia during myocardial ischemia and reperfusion in cats.Journal of Clinical Investigation, 1980