Biocatalytic membrane: Go far beyond enzyme immobilization

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Abstract
Biocatalytic membrane takes advantages of reaction–separation integration as well as enzyme immobilization, which has attracted increasing attentions in online detection and biomanufacturing. However, the high preparation cost, inferior comprehensive performance, and low stability limit its applications. Thus, besides enzyme immobilization, more efforts should be made in biocatalytic membrane configuration design for a specific application to enhance the synergistic effect of reaction and separation and improve its operating stability. This review summarized the recent progress on biocatalytic membrane preparation, discussed different membrane configurations for various applications, finally proposed several challenges and possible solutions, which provided directions and guides for the development and industrialization of biocatalytic membrane.
Funding Information
  • National Natural Science Foundation of China (21878306)
  • Youth Innovation Promotion Association of the Chinese Academy of Sciences (2017069)

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