The natural substrate for nitric oxide synthase activity
Authors:
- 25 May 2001
- journal article
- research article
- Published by Wiley in Cell Biochemistry and Function
- Vol. 19 (4) , 277-280
Abstract
There has been little evidence to indicate that arginine is the natural substrate for generating nitric oxide synthase (NOS) activity. It is now shown that carnosine, which is widely distributed in tissues, is likely to be the true substrate. In tissue sections it gives a stronger NOS reaction than does arginine. Copyright © 2001 John Wiley & Sons, Ltd.Keywords
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