Alkylation of 2-Phenyl-4-quinolones: Synthetic and Structural Studies.
Authors:
- 1 January 2001
- journal article
- Published by Pharmaceutical Society of Japan in Chemical and Pharmaceutical Bulletin
- Vol. 49 (10) , 1352-1355
Abstract
The alkylation of 2-phenyl-4-quinolones was investigated and showed that the N-alkylation versus O-alkylation is highly dependent on whether C-5 is hydroxylated or not. N-Alkylation is favoured by the presence of a 5-hydroxyl group. The synthetic and the NMR structural studies are reported.Keywords
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