Assessment of the Use of a Selection of Natural Deep Eutectic Solvents in the Extraction of Polar Bioactive Compounds from Orange Peel

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Abstract
The reuse of food chain residues is topical. This revaluation can extract bioactive compounds from these residues. However, extraction involves chemicals that cause environmental damage. In the present work, an experimental design with natural deep eutectic solvents (NADES) has been carried out for extracting bioactive compounds from orange peel residues. NADES have a very low environmental impact. The tests were performed with five different NADES, mixed with 70% water. The results were compared with ethanol–water 50%, v:v, showing that NADES solvents provided better extraction of phenolic compounds and antioxidant capacity. The shelf-life of the extracts was also evaluated, based on the above tests, for 4 weeks, finding significant changes from day 15 of storage at 4 °C.

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