ODGNet: a deep learning model for automated optic disc localization and glaucoma classification using fundus images

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Abstract
Glaucoma is one of the prevalent causes of blindness in the modern world. It is a salient chronic eye disease that leads to irreversible vision loss. The impediments of glaucoma can be restricted if it is identified at primary stages. In this paper, a novel two-phase Optic Disk localization and Glaucoma Diagnosis Network (ODGNet) has been proposed. In the first phase, a visual saliency map incorporated with shallow CNN is used for effective OD localization from the fundus images. In the second phase, the transfer learning-based pre-trained models are used for glaucoma diagnosis. The transfer learning-based models such as AlexNet, ResNet, and VGGNet incorporated with saliency maps are evaluated on five public retinal datasets (ORIGA, HRF, DRIONS-DB, DR-HAGIS, and RIM-ONE) to differentiate between normal and glaucomatous images. This study’s experimental results demonstrate that the proposed ODGNet evaluated on ORIGA for glaucoma diagnosis is the most predictive model and achieve 95.75, 94.90, 94.75, and 97.85% of accuracy, specificity, sensitivity, and area under the curve, respectively. These results indicate that the proposed OD localization method based on the saliency map and shallow CNN is robust, accurate and saves the computational cost.
Funding Information
  • China National Key R&D Program (2018YFB0803600)
  • Natural Science Foundation of China (61701009, 61801008)
  • The Beijing Science and Technology Planning Program of China (Z171100004717001)
  • Beijing Natural Science Foundation (4172002, L172049)
  • Scientific Research Common Program of Beijing Municipal Commission of Education (KM201910005025)
  • Chinese Postdoctoral Science Foundation (2020M670074)

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