Ten-Year Follow-up of Persons With Sun-Damaged Skin Associated With Subsequent Development of Cutaneous Squamous Cell Carcinoma
Open Access
- 1 May 2021
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Dermatology
- Vol. 157 (5) , 559-565
Abstract
Actinic keratoses (AKs) develop from sun exposure and affect more than 10% of the US population.1-3 A key risk factor for cutaneous squamous cell carcinoma (cSCC) is cumulative sun exposure.4 Although AKs are easily detected and treated, the extent to which they serve as a proxy for sun-damaged skin has not been adequately established.3 Estimates of the risk of cSCC after AK diagnosis have been based on short-term studies, and further investigation is needed to establish guidelines to standardize the frequency of skin surveillance to reduce cSCC morbidity and mortality.5 We conducted a large, community-based, matched longitudinal cohort study to assess cSCC risk for 10 years after the diagnosis of AK.Keywords
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