Brief Communication: Tumor Suppression by a Lymphokine Released Into the Circulation of Mice With Delayed Hypersensitivity 2

Authors:
  • SSS. B. Salvin
    S. B. Salvin
  • JYJ. S. Youngner
    J. S. Youngner
  • JNJane Nishio
    Jane Nishio
  • RNRuth Neta
    Ruth Neta

Abstract
Lymphokines such as migration inhibitory factor and type II interferon were released into the circulation of tuberculin-sensitive mice after iv injection of old tuberculin. Daily administration of such sera into the tumor sites of mice given implants of sarcoma MC-36 markedly suppressed tumor growth.