Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: Report from a phase I/II trial

Authors:
  • JFJavier Figueredo
    Javier Figueredo
  • MCMauricio Catala
    Mauricio Catala
  • GSGonzález Sandra
    González Sandra
  • JSJulio C. Selva
    Julio C. Selva
  • TCTania M. Cruz
    Tania M. Cruz
  • CTCarolina Toledo
    Carolina Toledo
  • SSSergio Silva
    Sergio Silva
  • YPYanet Pestano
    Yanet Pestano
  • MRMayra Ramos
    Mayra Ramos
  • ILIdrissa Leonard
    Idrissa Leonard
  • OTOlga Torres
    Olga Torres
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Abstract
The poor prognosis of patients with high-grade glioma has led to the search for new therapeutic strategies. More than half of these tumours over-express Epidermal Growth factor Receptor (EGFR). h-R...