The Structural Biology of Expression and Function of Tissue Factor

Authors:
  • TEThomas S Edgington
    Thomas S Edgington
  • NMNigel Mackman
    Nigel Mackman
  • KBKorbinian Brand
    Korbinian Brand
  • WRWolfram Ruf
    Wolfram Ruf
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Abstract
Analysis of the structural biology of TF provides insights into the both the expression of the gene and the function of this cell surface receptor in the initiation of the coagulation protease cascades. The advance of information may permit inferential hypotheses for the structural biology of other cofactor regulated catalytic steps in blood coagulation.