Abstract
Supplementary Figure S1. MR images of patient P05 with locally advanced clival chordoma. Brain MRI before treatment (A-C) shows left cavernous since disease (arrows), 6 months after initiation of high-dose pemetrexed (D-F), and 12 months after treatment initiation (G-J) showing shrinkage of enhancing tumor on axial post contrast T1 sequences (A, D, G), axial FLAIR (B, E, H) and axial T2 (C, F, I).