The landscape of cancer-associated fibroblasts in colorectal cancer liver metastases
Authors:
Open Access
- 31 October 2022
- journal article
- research article
- Published by Ivyspring International Publisher in Theranostics
- Vol. 12 (17) , 7624-7639
Abstract
Rationale: Patients with colorectal cancer die mainly due to liver metastases (CRC-LM). Although the tumor microenvironment (TME) plays an important role in tumor development and therapeutic response, our understanding of the individual TME components, especially cancer-associated fibroblasts (CAFs), remains limited.Keywords
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