Molecular modeling of γ-lactam analogues of β-lactam antibacterial agents: synthesis and biological evaluation of selected penem and carbapenem analoques
Authors:
- 1 January 1989
- journal article
- research article
- Published by Elsevier in Tetrahedron
- Vol. 45 (7) , 1905-1928
Abstract
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This publication has 65 references indexed in Scilit:
- The acylating potential of .gamma.-lactam antibacterials: base hydrolysis of bicyclic pyrazolidinonesJournal of Medicinal Chemistry, 1988
- Strategic approaches to drug design. II. Modelling studies on phosphodiesterase substrates and inhibitorsJournal of Computer-Aided Molecular Design, 1987
- Computer‐Assisted Molecular Design (CAMD)—An OverviewAngewandte Chemie International Edition, 1987
- γ-Lactam analogues of penicillanic and carbapenicillanic acidsJournal of the Chemical Society, Chemical Communications, 1983
- The penems, a new class of .beta.-lactam antibiotics. 2. Total synthesis of racemic 6-unsubstituted representativesJournal of the American Chemical Society, 1979
- Ground states of molecules. XXVII. MINDO/3 calculations for carbon, hydrogen, oxygen, and nitrogen speciesJournal of the American Chemical Society, 1975
- Ground states of molecules. XXVIII. MINDO/3 calculations for compounds containing carbon, hydrogen, fluorine, and chlorineJournal of the American Chemical Society, 1975
- Molecular architecture of the cephalosporins. Insights into biological activity based on structural investigationsJournal of the American Chemical Society, 1970
- The Synthesis of Analogs of Penicillin.1a IJournal of the American Chemical Society, 1953
- Studies on the Mucohalic Acids. II. The Synthesis of Fused α-Lactam-thiazolidines Related to Penicillin1Journal of the American Chemical Society, 1952