De Novo Design of α-Amylase Inhibitor: A Small Linear Mimetic of Macromolecular Proteinaceous Ligands
Authors:
- Manfred PavlíkMPManfred Pavlík
- Martin HornMHMartin Horn
- Michael MarešMMMichael Mareš
- 1 December 2005
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 12 (12) , 1349-1357
Abstract
No abstract availableKeywords
Funding Information
- Ministerstvo Školství, Mládeže a Tělovýchovy (OCD16.001, Z40550506)
- Grantová Agentura České Republiky (203/02/P081)
This publication has 34 references indexed in Scilit:
- Proteinaceous α-amylase inhibitorsBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2004
- Review of acarbose therapeutic strategies in the long-term treatment and in the prevention of type 2 diabetesInt. Journal of Clinical Pharmacology and Therapeutics, 2003
- Plant α‐amylase inhibitors and their interaction with insect α‐amylasesEuropean Journal of Biochemistry, 2002
- Alpha-amylase inhibitors selected from a combinatorial library of a cellulose binding domain scaffoldProteins: Structure, Function, and Bioinformatics, 2000
- Specific inhibition of insect α-amylases: yellow meal worm α-amylase in complex with the Amaranth α-amylase inhibitor at 2.0 Å resolutionStructure, 1999
- A novel strategy for inhibition of α-amylases: yellow meal worm α-amylase in complex with the Ragi bifunctional inhibitor at 2.5 å resolutionStructure, 1998
- Barley α-amylase bound to its endogenous protein inhibitor BASI: crystal structure of the complex at 1.9 å resolutionStructure, 1998
- Substrate mimicry in the active center of a mammalian α amylase: structural analysis of an enzyme–inhibitor complexStructure, 1996
- The Crystal Structure of Porcine Pancreatic α-Amylase in Complex with the Microbial Inhibitor TendamistatJournal of Molecular Biology, 1995
- Chemistry and Biochemistry of Microbial α‐Glucosidase InhibitorsAngewandte Chemie International Edition, 1981