Targeted inhibition of ULK1 enhances daunorubicin sensitivity in acute myeloid leukemia
Authors:
- Gan ZhouGZGan Zhou
- Shan CaoSCShan Cao
Open Access
- 1 February 2020
- journal article
- research article
- Published by Elsevier in Life Sciences
- Vol. 243, 117234
Abstract
No abstract availableKeywords
Funding Information
- Chinese National Science Foundation (81503073,, 81170091, 81422052)
- Special topic of the major subject of national science and technology (2012ZX09509-107)
- National Science and Technology Major Project (2017ZX09304014)
- Hunan Sci and Tech Innovation Project (2018SK52612)
This publication has 46 references indexed in Scilit:
- Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cellsInternational Journal of Oncology, 2016
- Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 SubstratesMolecular Cell, 2015
- Prevention of Anthracycline-Induced CardiotoxicityJACC, 2014
- Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast CancerClinical Cancer Research, 2014
- Inhibition of mTOR-Dependent Autophagy Sensitizes Leukemic Cells to Cytarabine-Induced Apoptotic DeathPLOS ONE, 2014
- Distinct functions ofUlk1andUlk2in the regulation of lipid metabolism in adipocytesAutophagy, 2013
- Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitroActa Pharmacologica Sinica, 2012
- HMGB1 Promotes Drug Resistance in OsteosarcomaCancer Research, 2012
- Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to MitophagyScience, 2011
- Expert opinion on the use of anthracyclines in patients with advanced breast cancer at cardiac riskAnnals of Oncology, 2009