Fatty acid pattern of red blood cell membranes and risk of ischemic brain infarction: a case-control study.

Authors:
  • SRS Ricci
    S Ricci
  • LPL Patoia
    L Patoia
  • MBM Berrettini
    M Berrettini
  • LBL Binaglia
    L Binaglia
  • MSM G Scarcella
    M G Scarcella
  • GBG Bucaneve
    G Bucaneve
  • ICI Carloni
    I Carloni
  • LAL Agostini
    L Agostini
  • PPP Parise
    P Parise
  • VSVenø S
    Venø S
  • BCBork C
    Bork C
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Abstract
The fatty acid composition of red blood cell membranes (which reflects dietary fat intake) was studied in 28 male patients with recent (less than 3 days) ischemic stroke and 56 matched controls. Fifteen fatty acids were measured by means of chromatographic analysis. Percentages of linoleic, 22:5, and 22:6 acids were significantly lower in red blood cell membranes of stroke patients than in those of matched controls. The results suggest that a low unsaturated fatty acid diet could be an independent risk factor for ischemic brain infarction.

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